HPV DNA Test and Vaccine

Silivri-Genital-Sigil

Human Papillomavirus (HPV) is one of the most common sexually transmitted infections and includes more than 200 genotypes, some of which are associated with genital warts, cervical precancer (CIN), and cervical cancer. Accurate diagnosis with HPV DNA testing and timely vaccination are the most effective strategies for prevention, early detection, and long-term protection.

At Saga Clinic, we offer comprehensive HPV screening, genotype identification, and individualized vaccination plans based on international guidelines to ensure complete and evidence-based patient care.


What Is the HPV DNA Test?

The HPV DNA test detects the genetic material of the virus and identifies specific HPV types, especially high-risk strains associated with cervical cancer (such as HPV 16 and 18).

Why HPV DNA Testing Is Important

  • Detects high-risk HPV infections early
  • Identifies the exact HPV genotype
  • Guides the need for colposcopy and follow-up
  • Helps assess the risk of cervical dysplasia (CIN)
  • Essential for women with abnormal Pap smear results

→ Read More --> HPV Types, HPV in Women, CIN Management, Colposcopy


How Is the HPV DNA Test Performed?

For Women

A cervical sample is collected using a soft brush during a pelvic examination.
This test:

  • Is painless
  • Can be performed at the same time as a Pap smear
  • Detects both low-risk and high-risk HPV types

For Men

A sample is taken from:

  • The penile shaft
  • The glans
  • The scrotum
  • Or directly from a visible wart (if present)

→ Read More --> HPV in Men

Men often carry HPV without symptoms, so DNA testing is recommended in cases of recurrent warts or when the partner tests positive.


When Should You Have the HPV DNA Test?

HPV DNA testing is recommended if:

  • You have an abnormal Pap smear
  • You have a partner with HPV
  • You experience recurrent genital warts
  • You are over age 30 as part of routine screening
  • You have symptoms or risk factors for cervical lesions
  • You previously had CIN or cervical treatment (LEEP or laser therapy)

→ Read More --> HPV in Women


Understanding the Results

High-Risk HPV Positive

Indicates infection with a type associated with CIN or cervical cancer (e.g., HPV 16, 18).
Follow-up includes:

  • Colposcopy
  • Cervical biopsy when indicated
  • Closer surveillance

→ Read More --> CIN Management


Low-Risk HPV Positive

Associated with genital warts (e.g., HPV 6, 11).
These types do not cause cervical cancer.

→ Read More --> Genital Wart Treatment Methods


HPV Negative

No HPV detected and very low risk of cervical pathology at that time.
Routine screening intervals may be extended according to age and guidelines.


HPV Vaccine

The HPV vaccine is the most effective tool for preventing HPV-related diseases, including:

  • Cervical cancer
  • Vulvar and vaginal cancers
  • Anal cancer
  • Genital warts

9 valent vaccine protects against the 9 most clinically significant HPV types:
6, 11, 16, 18, 31, 33, 45, 52, and 58.


Who Should Receive the HPV Vaccine?

Ideal Candidates

  • Adolescents aged 9–14 (best immune response)
  • Women aged 15–45
  • Men aged 15–45
  • Individuals with no HPV or recent HPV infection
  • Patients with genital warts or recurrent infections (for prevention of new infections)

→ Read More --> HPV Vaccine


Vaccine Schedule

Ages 9–14

  • 2 doses (0 and 6–12 months)

Ages 15–∞

  • 3 doses (0, 2, and 6 months)

Once the series is completed, no booster doses are currently recommended.


Can You Be Vaccinated If You Already Have HPV?

Yes.
The vaccine does not treat existing HPV, but it prevents infection with other high-risk types and reduces the likelihood of new lesions or warts.
Vaccination is still strongly recommended for:

  • Patients with HPV positivity
  • Individuals with genital warts
  • Patients previously treated for CIN

Safety and Side Effects

HPV vaccines have an excellent safety profile with millions of doses administered worldwide.

Common, mild side effects include:

  • Arm soreness
  • Redness at injection site
  • Low-grade fever
  • Fatigue

Severe reactions are extremely rare.


Saga Clinic’s Approach to HPV Screening and Prevention

At Saga Clinic, HPV management is approached with precision and comprehensive care.
We provide advanced HPV DNA testing, genotype-specific counseling, and tailored vaccination plans. Our team ensures that each patient receives accurate diagnosis, early intervention when needed, and long-term protection through vaccination—following leading international guidelines and the latest scientific data.


Contact & Appointments

For appointment requests or medical inquiries, please contact us using the options below.

📞 Clinic Phone (Office Hours)
+355 69 836 1565
Available Monday–Saturday, 09:00–16:00.

💬 WhatsApp (Outside Office Hours)
+355 69 456 4467
Available outside office hours via WhatsApp Message only.

Author: Asst. Prof. Eser Ağar, MD — Obstetrician and Gynecologist

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This page is for informational purposes and does not replace examination and physician evaluation.

Medically reviewed: Asst. Prof. Eser Ağar, MD —